Antimicrobial hydrogels based on 2-hydroxyethyl methacrylate and itaconic acid containing silver(I) ion
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منابع مشابه
Fabrication and Evaluation of 2-Hydroxyethyl Methacrylate-co-Acrylic Acid Hydrogels for Sustained Nicorandil Delivery
Purpose: To fabricate and evaluate oral 2-hydroxyethyl methacrylate-co-acrylic acid hydrogels as a drug delivery system for sustained release of nicorandil. Methods: HEMA-co-AA hydrogels using different monomer concentrations were prepared by free radical polymerization. N, N-methylene bis acrylamide (MBA) was used as crosslinker and potassium persulphate (KPS) as initiator. Nicorandil (20 mg) ...
متن کامل2,3-Dihydroxypropyl methacrylate and 2-hydroxyethyl methacrylate hydrogels: gel structure and transport properties
The drying kinetics were examined in four cross-linked polymers that form hydrogels: 2,3-Dihydroxypropyl methacrylate (DHPMA) and 2-hydroxyethyl methacrylate (HEMA) and two random copolymers, with one-to-one and three-to-one HEMA-to-DHPMA molar ratios. The hydrogels were saturated with buffered, isotonic saline solution and deionized water; weight loss kinetics were monitored at temperatures fr...
متن کاملIntra and intermolecular relaxations 2,3-dihydroxypropyl methacrylate and 2-hydroxyethyl methacrylate hydrogels
The dynamic mechanical transitions present in the 2-hydroxyethyl methacrylate (HEMA) and 2,3-dihydroxypropyl methacrylate (DHPMA) homopolymers and two random copolymers, with one-to-one and three-to-one HEMA-to-DHPMA molar ratios, were examined by analyzing the dry xerogels and hydrogels at various states of hydration. The temperatures of the primary a transition and the secondary b and g trans...
متن کاملTailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels.
Swelling pressure measurements were performed on degrading dextran hydroxyethyl methacrylate (dex-HEMA) hydrogels. In these networks, the cross-links are hydrolyzable carbonate ester bonds formed between methacrylate groups and dextran molecules. It is demonstrated that dex-HEMA gels made in the presence of a known amount of free dextran chains exhibit osmotic properties similar to those of par...
متن کاملAntimicrobial peptide incorporated poly(2-hydroxyethyl methacrylate) hydrogels for the prevention of Staphylococcus epidermidis-associated biomaterial infections.
The effectiveness of the antimicrobial peptide maximin-4, the ultrashort peptide H-Orn-Orn-Trp-Trp-NH(2), and the lipopeptide C(12)-Orn-Orn-Trp-Trp-NH(2) in preventing adherence of pathogens to a candidate biomaterial were tested utilizing both matrix- and immersion-loaded poly(2-hydroxyethyl methacrylate) (poly(HEMA)) hydrogels. Antiadherent properties correlated to both the concentration rele...
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ژورنال
عنوان ژورنال: Tehnika
سال: 2014
ISSN: 0040-2176
DOI: 10.5937/tehnika1404563m